Honeywell PD45 Printhead vs. PD45S Printhead: What Is the Difference and Are They Compatible?
Introduction
Honeywell PD45 and PD45S are industrial barcode printers designed for applications including manufacturing, logistics, retail, healthcare, and transportation. Both models support direct thermal and thermal transfer printing and are available with 203 dpi and 300 dpi print resolutions.
Because the two printers belong to the same product family and have very similar specifications, a common question is:
Can a Honeywell PD45 printhead be used on a PD45S, or vice versa?
The short answer is:
Do not assume that PD45 and PD45S printheads are interchangeable.
Although they share the same resolution options and Honeywell lists both models in the same product family, Honeywell assigns different printhead kit part numbers to PD45 and PD45S. The correct replacement should therefore be selected according to the printer model and printhead resolution.


1. Honeywell PD45 vs. PD45S: Basic Difference
The main difference between PD45 and PD45S is not simply the printhead technology. The two printers are different configurations within the same Honeywell industrial printer platform.
Honeywell states that both PD45 and PD45S use thermal transfer and direct thermal printing, with available resolutions of **203 dpi and 300 dpi**. Their maximum print speed is listed as up to 250 mm/s, or approximately 10 ips.
However, their user interfaces and positioning performance are different.
| Feature | Honeywell PD45 | Honeywell PD45S |
| Printer type | Industrial barcode printer | Industrial barcode printer |
| Print technology | Direct Thermal / Thermal Transfer | Direct Thermal / Thermal Transfer |
| Resolution | 203 dpi / 300 dpi | 203 dpi / 300 dpi |
| Maximum print speed | Up to 10 ips | Up to 10 ips |
| Display | 2.36" keypad LCD | 3.5" full-touch color LCD |
| Minimum label height | 5 mm | 5 mm |
| Positioning accuracy | Approx. 0.75 mm | Approx. 0.5 mm |
| 203 dpi printhead | 50178577-001 | 50177476-001 |
| 300 dpi printhead | 50178578-001 | 50178575-001 |
Honeywell specifically identifies the PD45S as having a 3.5-inch full-touch color LCD, while the PD45 uses a 2.36-inch keypad LCD. Honeywell also lists vertical positioning accuracy of 0.5 mm for PD45S versus 0.75 mm for PD45.
2. PD45 and PD45S Printhead Comparison
This is the most important information for replacement and aftermarket sourcing.
| Resolution | Honeywell PD45 | Honeywell PD45S |
| 203 dpi | 50178577-001 | 50177476-001 |
| 300 dpi | 50178578-001 | 50178575-001 |
| Printer family | PX240 / PD45 | PX240S / PD45S |
| Recommended replacement | Match PD45 part number | Match PD45S part number |
Honeywell's official accessory documentation clearly separates these four printhead part numbers by printer model.
This means that PD45 and PD45S should not be treated as having the same replacement printhead simply because both printers support 203 dpi and 300 dpi.
3. Are PD45 and PD45S Printheads Compatible?
The short answer: Not officially interchangeable.
For example:
PD45 203 dpi
→ 50178577-001
PD45S 203 dpi
→ 50177476-001
Both are nominally 203 dpi, but Honeywell assigns them different part numbers.
The same applies to the 300 dpi versions:
PD45 300 dpi
→ 50178578-001
PD45S 300 dpi
→ 50178575-001
Therefore, same resolution does not mean same printhead.
This is an important distinction for distributors, maintenance companies, and replacement-part suppliers.
Final Recommendation
Do not select a PD45 or PD45S printhead based only on DPI.
For replacement, always verify:
Printer model → Resolution → Original Part Number
This is the safest way to avoid purchasing a printhead that appears similar but is not the correct replacement.
If you are sourcing Honeywell PD45 or PD45S printheads in bulk, providing the printer model, DPI, and original printhead part number to the supplier is recommended. This can significantly reduce compatibility and installation risks.

